食管中下段癌同期放化疗后经左胸颈切除器械吻合的疗效

Resection and stapler anastomosis via left cervicothoracic approach for the treatment of distal esophageal cancer

  • 摘要: 目的:探讨食管中下段癌同期放化疗后经左胸颈切除器械吻合的疗效。
    方法:回顾性分析2000年1月至2011年12月解放军第一○五医院收治的86例食管鳞癌患者的临床资料。所有患者于术前放化疗后接受左胸颈两切口左颈部食管胃端侧器械吻合并行三野淋巴结清扫。术后通过门诊复查或每次入院定期复查进行随访,随访时间截至2011年12月。采用KaplanMeier法计算生存率。
    结果:82例患者手术顺利,肿瘤切除率达95.3%(82/86)。82例患者AJCC分期Ⅱa期20例、Ⅱb期37例、Ⅲ期25例。术后病理检查结果证实淋巴结有转移者42例,分组标记证实颈、胸、腹3组淋巴结转移率分别为3.7%(3/82)、53.7%(44/82)、22.0%(18/82)。86例患者并发症发生率为13.4%(11/82),死亡1例。74例患者随访4个月至10年,中位随访时间为7.6年。19例Ⅱa期患者术后1、3、5年生存率分别为88%、83%、57%,34例Ⅱb期患者分别为82%、68%、43%,21例Ⅲ期患者分别为56%、25%、16%。
    结论:食管中下段癌放化疗后经左胸颈切除器械吻合具有病灶切除彻底,切缘癌细胞残留率低,严重并发症少,近期疗效好的优点。

     

    Abstract: Objective To investigate the efficacy of resection and stapler anastomosis via left cervicothoracic approach for the treatment of distal esophageal cancer.
    Methods The clinical data of 86 patients with esophageal squamous cell carcinoma who were admitted to the No.105 Hospital of PLA were retrospectively analyzed. All patients received preoperative radiochemotherapy followed by radical esophagectomy and esophagogastric end to side anastomosis via left cervicothoracic approach. All the patients were followed up via out patient examination till December 2011. The survival rate was calculated by Kaplan Meier method.
    Results The surgery was successfully carried out on 82 patients, and the resection rate was 95.3%(82/86). According to AJCC staging, there were 20 patients in stage Ⅱa, 37 patients in stage Ⅱb, 25 patients in stage Ⅲ. Forty two patients were diagnosed with lymph node metastasis, and the metastatic rates of lymph nodes in the neck, chest and abdomen were 3.7%(3/82), 53.7%(44/82) and 22.0%(18/82), respectively. The complication rate was 13.4%(11/82), and 1 patient died postoperatively. The 1 , 3 , 5 year survival rates were 88%, 83% and 57% for patients in stage Ⅱa, 82%, 68% and 43% for patients in stage Ⅱb, 56%, 25% and 16% for patients in stage Ⅲ. 〖HQ〗
    Conclusions Resection and stapler anastomosis via left cervicothoracic aproach for the treatment of distal esophageal cancer has the advantages of low complication rate, high resection rate and excellent curative effect.

     

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